Cushing's syndrome in dogs, also known as canine hyperadrenocorticism,

Canine hyperadrenocorticism is a hormonal disorder that affects dogs and other animals. It is caused by an overproduction of the hormone cortisol, which is produced by the adrenal gland. Cortisol plays a role in regulating many body processes, including metabolism, the immune system, and the stress response.

Symptoms of canine hyperadrenocorticism disease in dogs may include:

Increased thirst and urination
Increased appetite
Hair thinning
Thin, fragile skin that is easily bruised
Pot-bellied appearance
Lethargy
Panting
Weakness
Elevated liver enzyme ALP and GGT

Dog Cushing's syndrome can be caused by a variety of factors, including a tumour on the pituitary gland (more common) or adrenal gland, prolonged use of corticosteroid medications, or an adrenal gland disorder.

How is Cushing’s disease diagnosed?
Your veterinarian will do a physical exam and run blood tests to determine what may be causing your pet's symptoms as well as to rule out other health problems.

Your veterinarian may also run adrenal function tests, like an ACTH stimulation test

An ultrasound may help to rule out other conditions and often helps diagnose canine hyperadrenocorticism by the enlarged adrenal glands.

Treatment for canine hyperadrenocorticism

Typically, involves medications to suppress the production of cortisol, like Lysodren, Mitotane, or trilostane as well as other supportive care. In some cases, surgery may be necessary to remove a tumour or abnormal gland. It is important to work closely with a veterinarian to determine the appropriate treatment plan for your dog with canine hyperadrenocorticism.